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Does sodium bicarbonate increase gastrin concentrations in man?

The Effect of Sodium Bicarbonate on Serum Gastrin Concentrations in Man
Feurle GE. The Action of Antacids on Serum Gastrin Concentrations in Man. European Journal of Medicine (Klin Wschr) 1977; 55: 1039-1042

Methods:

• 8 patients received two doses of sodium bicarbonate.
• Each dose was 30 meq
• The doses were separated by 30 min

NOTE: Patients also received a similar amount of NaCl at a separate time which caused no change in Gastrin.

 

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