TOES Evaluations of Abstracts Submitted for the 69th Annual Scientific Meeting of the American College of Gastroenterology
American Journal of Gastroenterology, Vol. 99, No. 10, Suppl., 2004, ©2004 by Am. Coll. of Gastroenterology, ISSN 0002-9270/04/xx.xx, Published by Blackwell Publishing
October 29–November 3, 2004, Orlando, Florida
A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL DEMONSTRATING THE EFFECTIVENESS OF AN EDUCATIONAL INTERVENTION IN IMPROVING PROTON PUMP INHIBITOR DOSING HABITS.
Pezanoski JP, et al. Am J Gastro 2004:99 Suppl; A55.
Evidence-based info: A prospective, randomized controlled trial.
Type of Study: Independent
Sample size: n = 139
Background: Standard PPIs should be taken in association with a meal.
The meal stimulates parietal cells and more pumps can then be inhibited.
Primary finding: 8% took the PPI correctly at baseline, these groups were randomly divided into education and non-education.
The non-education group increased to 12% taking the PPI correctly (ns)
The education group increased to 23% taking PPI correctly.
Score of Study (TOES): = 70 out of 100
Is it consistent with what we already know? - Yes
How should this effect your practice?- When you choose a PPI don’t expect your patient take it as they should even if you educate them.
- You can tell them to do whatever you want to but even after a really good educational program only 23% will do it and who knows for how long.
- However, you should ask your patient about when they take their PPI if they continue to have symptoms after being on it for a while.
- Tell them that taking it within 1/2 hr of breakfast gets the most bang for the dose.